Antibody-mediated enhancement of Wesselsbron virus in P388D1 cells

FAGBAMI, A. H.; HALSTEAD, S. B.

Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/1868

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DC Field	Value	Language
dc.contributor.author	FAGBAMI, A. H.	-
dc.contributor.author	HALSTEAD, S. B.	-
dc.date.accessioned	2023-02-02T10:33:02Z	-
dc.date.available	2023-02-02T10:33:02Z	-
dc.date.issued	1986-09	-
dc.identifier.citation	Afr. J. Med. med. Sci. (1986) 15(3/4): 103-107.	en_US
dc.identifier.issn	1116-4077	-
dc.identifier.uri	http://adhlui.com.ui.edu.ng/jspui/handle/123456789/1868	-
dc.description	Article	en_US
dc.description.abstract	Antibody-mediated enhancement of Wesselsbron virus was investigated in P388D1, cell cultures. Virus infection was enhanced in culture by various dilutions of homologous and heterologous flavivirus antibody. Highest enhancement ratios and enhancing antibody litres were obtained with the homologous antibody. Enhancement of Wesselsbron virus infection in P388D1 cultures was also dependent on the multiplicity of infection (MOI) used: cultures infected at the lowest MOI produced the highest enhancement ratios. Of the four heterologous flavivirus IMAF tested for ability to enhance Wesselsbron virus infection. Potiskum virus antibody produced highest fold enhancement and possessed the highest enhancing antibody title. Zika, Uganda S and Dakar bat IMAF produced lower fold enhancement and had lower enhancing antibody titres.	en_US
dc.description.sponsorship	COLLEGE OF MEDICINE	en_US
dc.language.iso	en	en_US
dc.publisher	COLLEGE OF MEDICINE	en_US
dc.subject	Antibody	en_US
dc.subject	Virus infection	en_US
dc.subject	Wesselsbron virus	en_US
dc.subject	Infection	en_US
dc.title	Antibody-mediated enhancement of Wesselsbron virus in P388D1 cells	en_US
dc.type	Article	en_US
Appears in Collections:	African Journal of Medicine and Medical Sciences

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