Dysgenesis of the corpus callosum: Computed tomographic changes

Abstract

The CT findings in 32 cases of DCC are presented classifying them into three groups: Type I: Anatomical changes primarily due to callosal dysgenesis. Type II: Associated central nervous system anomalies. Type III: Incidental findings. The findings were compared with those of others. This study confirms that the CT findings which are of a high diagnostic index are those of Type I changes which include enlargement and elongation of the interventricular foramen, enlargement and continuity of the interhemispheric fissure with the third ventricle, which is invariably enlarged, elevation and anterior displacement of the third ventricle. Separation and parallelism of the lateral ventricle is also one of the most diagnostic features. Three rare syndromes (Soto's, Aicardis's and De Morsier's) and the rare occurrence of associated teratoma which were encountered as part of the associated congenital abnormalities are mentioned. The embryological basis of the CT findings is discussed.