Possible evidence of angiotensin II and endogenous opioid modulation of novelty-induced rearing in the rat

Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2076

Title:	Possible evidence of angiotensin II and endogenous opioid modulation of novelty-induced rearing in the rat
Authors:	AJAYI, A.A UKPONMWAN, O.E
Keywords:	angiotensin II endogenous Rats
Issue Date:	Sep-1994
Publisher:	Spectrum Books Limited
Citation:	Afr. J. Med. med. Sci. (1994) 23, 287-290
Abstract:	Rats treated with captopril (CAP, 10mg/k^ i.p) naltrexone (Nalx 0.1mg/kg i.p) and saralasinc (100ug/kg i.p) displayed significantly less novelty-induced rearing (NIR) compared to saline injected animals. Naltrexone potentiated the inhibitory effect of CAP on NIR. Pretreatment with NALX did not alter SARA-induced decrease in NIR. It is suggested that the endogenous release of All and/or opioids somehow modulate basal rearing activity.
Description:	Article
URI:	http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2076
ISSN:	1116-4077
Appears in Collections:	African Journal of Medicine and Medical Sciences

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