Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2102
Title: Incidence of dual presence of antibodies to HIVi and HIV2 in seropositive cases seen in Ibadan, Nigeria
Authors: SHOKUNBI, W.A.
SALIU, I.
ESSIEN, E.M.
Keywords: Incidence
antibodies
HIV-1 and HIV-2
seropositive cases
Issue Date: Sep-1995
Publisher: SPECTRUM BOOKS LIMITED.
Citation: Afr. J. Med. med. Sci. Vol. 24:249-253
Abstract: Between July 1987 and December 1988, sera from 6,385 individuals were screened for HIV| but only 1,861 of these samples were screened for HIV2. Majority of those screened for HIV infection (89.7%) were blood donors, 4.9% were international traveller^volunteers, 3.8% were patients (i.e. those with haemalological malignancies, multiply transfused patients and those suspected of having HIV infection), and the rest (1.6%) were female sex workers. Screening for HIV| antibody was done using Welcozyme anti-HTLV III (Wellcome Diagnostics, Dartford, England) or Elavia I (Diagnostics Pasteur, Mames La Coquette, France). ELAVIA Ac-Ab-Ak II was used to detect HIV2. The confirmatory test employed was western blot, using LAV Blot I and LAV Blot II (Diagnostic Pasteur, Mames La Coquette, France). The seroprevalence rate for HIVi in the blood donors was 0.51% while that of HIV2 was 0.33%. The seroprevalence rates for HIV| and HIV2 amongst the adult travelfcrs were 1.64% and 0.55% respectively and the comparative rates in the multiply transfused patients (including those with haemalological malignancies) were 1.23% each. All the HIV2 positive cases in this group had refractory anaemia. In those suspected of having HIV infection, the seroprevalence rate of HIV 1 was 2.94% and no patient in this group had HIV2. vidence of dual infection by HIVi and HIV2 was obtained from 18.5% of the seropositive individuals. The dual infection rate in seropositive Nigerians is similar to that reported for some West African countries. We would strongly suggest that all blood samples for HIV tests in Nigerians should be screened for both HIV 1 and HIV2. The two blood donors with evidence of dual infection could not be contacted due to fictitious addresses. The only patient with a dual infection has refractory anaemia and he is still being followed up but has not yet developed full-blown AIDS.
Description: Article
URI: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2102
ISSN: 1116-4077
Appears in Collections:African Journal of Medicine and Medical Sciences

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