SERUM METFORMIN LEVELS IN NIGERIANS WITH NON-INSULINDEPENDENT DIABETES MELLITUS

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DC Field	Value	Language
dc.contributor.author	IYUN, A. O.	-
dc.contributor.author	FAMUYIWA, O.O	-
dc.date.accessioned	2024-07-26T14:17:44Z	-
dc.date.available	2024-07-26T14:17:44Z	-
dc.date.issued	1982	-
dc.identifier.citation	Afr. J. Med. mcd. Sci. (1982) II, 171-174	en_US
dc.identifier.issn	1116-4077	-
dc.identifier.uri	http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2440	-
dc.description	ARTICLE	en_US
dc.description.abstract	'Steady state' serum concentrations of metformin have been measured in sixteen Nigerians with non-insulin-dependent diabetes mellitus. There was a thirty-eight-fold variation in the serum levels (50 1886 ng/ml). The mean serum level of metformin was 512 ± 485.2 ng/ml. This compared favourably with the mean levels (382.3 ± 76.9 ng/ml) obtained in a similar study in Italians. The observed levels however fell far short of those expected in patients on 1-5 g metformin daily. The role of poor bioavailability vis-a-vis poor patient compliance deserves further detailed pharmacokinetic study	en_US
dc.description.sponsorship	COLLEGE OF MEDICINE	en_US
dc.language.iso	en	en_US
dc.publisher	BLACKWELL SCIENTIFIC PUBLICATIONS	en_US
dc.subject	study	en_US
dc.subject	diabetes mellitus	en_US
dc.subject	serum	en_US
dc.subject	Nigerians	en_US
dc.title	SERUM METFORMIN LEVELS IN NIGERIANS WITH NON-INSULINDEPENDENT DIABETES MELLITUS	en_US
dc.type	Article	en_US
Appears in Collections:	African Journal of Medicine and Medical Sciences

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