Please use this identifier to cite or link to this item: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2708
Title: Clinical study of cerebral malaria in African children
Authors: Sowunmi, A.
Keywords: cerebral malaria
convulsions
african
Children
Issue Date: 1997
Publisher: COLLEGE OF MEDICINE
Citation: Afr. J. Med. med. Sci. (1997) 26, 9-11
Abstract: Of 51 consecutive children with cerebral malaria, fever, convulsions, and drowsiness were the commonest presenting symptoms. Decerebrate and decorticate postures and absent cornea reflex were the commonest brain stem signs. Opening lumbar cerebrospinal (CSF) pressure was raised in all but one of 24 children in whom it was reliably measured [mean 15.2 5.7 mmHg, range 6-24]. Hyponatraemia occurred in 17 (33%). Acute renal failure was not uncommon; the combination of hypercreatininaemia (plasma creatinine > 100 /xmol/L)and hyperkalemia (plasma potassium > 6.0/zmol/L) was fatal in 5 out of 7 patients in whom it occurred. Disturbances of acid-base status were present in all 40 children in whom it was assessed on admission. Mortality rate was 16% (8 patients). Neurological deficits occurred in 7 (14%) of the survivors and included cortical blindness [3], aphasia [3], hypertonia [3], hearing loss (2], and dystonia [1]. In addition to the present measures aimed at reducing morbidity and morality in children with cerebral malaria, efforts should be directed at rapid assessment of renal function and prompt correction of such dysfunction if found.
Description: Article
URI: http://adhlui.com.ui.edu.ng/jspui/handle/123456789/2708
ISSN: 1116-4077
Appears in Collections:African Journal of Medicine and Medical Sciences

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