Endocrine Disruptors-Arsenic, cadmium and lead in pre and postmenopausal black women with breast cancer

Abstract

Background: The involvement of toxic metals in adiposity lies been suggested to be contributory to the high incidence of breast cancer, particularly in sub-Saharan Africa. This study is aimed at evaluating scrum arsenic, cadmium and lead in relation to adiposity and blood pressure in Nigerian women with breast cancer. Methodology: The study comprised 85 women newly diagnosed with breast cancer protheraphy (cases) matched with 84 apparently healthy women without breast cancer (controls) according to age and menstrual phase. Arsenic (As), cadmium (Cd) and Lead (Pb) levels were determine d by atomic absorption spectrophotometry. Blood pressure and anthropometry were determined by standard methods. Data analyzed by Student's test and Pearson correlation coefficient were considered statistically significant.